2,511 research outputs found
High-Magnification Digital Image Correlation Techniques for Aged Nuclear Fuel Cladding Testing
Nuclear fuel cladding in light water reactors, often made of zirconium alloys, is naturally made more brittle by exposure to the water coolant during normal reactor operation. However, this embrittlement by zirconium hydrides changes the mechanical behavior of the cladding material, affecting how it will deform and what may cause it to fail. Because the cladding already has different properties in different material directions, mechanical testing also needs to be direction specific. In addition, to understand the effects that these microscale hydride features have, measurements of deforming cladding need to be at a microscale. This dissertation describes several high-magnification innovations and advancements in digital image correlation (DIC), a non-contact method for measuring displacement and strain of test specimens during experiments. First, a high-magnification UV lens is demonstrated to be capable of DIC measurements with improved spatial resolution and at high temperatures. Second, previously developed super resolution imaging techniques are applied to DIC measurements of directional ring test specimens, again improving resolution and measurement quality. Third, image capture settings are optimized to balance a tradeoff between poor depth of field and the diffraction of light, both of which cause blurred images and poorer DIC measurements. Fourth, several test arrangements are analyzed with computer modelling to determine the best method for directional tests of the cladding. Finally, the techniques are used to perform high-magnification tension tests for hydrided ring cladding specimens
Pyroelectric detectors
The multi-agency, long-term Global Change programs, and specifically NASA's Earth Observing system, will require some new and advanced photon detector technology which must be specifically tailored for long-term stability, broad spectral range, cooling constraints, and other parameters. Whereas MCT and GaAs alloy based photovoltaic detectors and detector arrays reach most impressive results to wavelengths as long as 12 microns when cooled to below 70 K, other materials, such as ferroelectrics and pyroelectrics, appear to offer special opportunities beyond 12 microns and above 70 K. These materials have found very broad use in a wide variety of room temperature applications. Little is known about these classes of materials at sub-room temperatures and no photon detector results have been reported. From the limited information available, researchers conclude that the room temperature values of D asterisk greater than or equal to 10(exp 9) cm Hz(exp 1/2)/W may be improved by one to two orders of magnitude upon cooling to temperatures around 70 K. Improvements of up to one order of magnitude appear feasible for temperatures achievable by passive cooling. The flat detector response over a wavelength range reaching from the visible to beyond 50 microns, which is an intrinsic advantage of bolometric devices, makes for easy calibration. The fact that these materials have been developed for reduced temperature applications makes ferro- and pyroelectric materials most attractive candidates for serious exploration
The Outbursts and Orbit of the Accreting Pulsar GS 1843-02 = 2S 1845-024
We present observations of a series of 10 outbursts of pulsed hard X-ray flux
from the transient 10.6 mHz accreting pulsar GS 1843-02, using the Burst and
Transient Source Experiment on the Compton Gamma Ray Observatory. These
outbursts occurred regularly every 242 days, coincident with the ephemeris of
the periodic transient GRO J1849-03 (Zhang et al. 1996), which has recently
been identified with the SAS 3 source 2S 1845-024 (Soffitta et al. 1998). Our
pulsed detection provides the first clear identification of GS 1843-02 with 2S
1845-024. We present a pulse timing analysis which shows that the 2S 1845-024
outbursts occur near the periastron passage of the neutron star's highly
eccentric (e = 0.88+-0.01) 242.18+-0.01 day period binary orbit about a high
mass (M > 7 solar masses) companion. The orbit and transient outburst pattern
strongly suggest the pulsar is in a binary system with a Be star. Our
observations show a long-term spin-up trend, with most of the spin-up occurring
during the outbursts. From the measured spin-up rates and inferred luminosities
we conclude that an accretion disk is present during the outbursts.Comment: Accepted for publication in Astrophysical Journa
A systematic review of biomarkers among hospitalized patients with COVID-19 predictive of venous thromboembolism: A communication from the Predictive and Diagnostic Variables Scientific and Standardization Committee of the ISTH
Background
Thrombosis is reported to occur more often among patients with COVID-19 than otherwise expected in the setting of viral pneumonia and sepsis. Systemic inflammatory biomarkers may be associated with venous thromboembolism (VTE) risk. The ISTH subcommittee on Predictive and Diagnostic Variables in Thrombotic Disease aimed to report the evidence on prognostic biomarkers for VTE in hospitalized patients with COVID-19.
Methods
Using a standardized Preferred Reporting Items for Systematic Reviews and Meta-analysis methodology, we conducted a systematic literature review to identify studies reporting prognostic biomarkers for VTE among hospitalized patients with COVID-19. Eligible studies included adults hospitalized with COVID-19 and reported the prognostic associations between any biomarker measured on admission, and the subsequent diagnosis of deep vein thrombosis or pulmonary embolism. Two authors reviewed titles and abstracts, and three authors extracted study data and performed review of bias. Results were displayed descriptively. Meta-analysis was not possible.
Results
From the initial 196 identified studies, full-text review was performed for 72 studies. Admission D-dimer levels were associated with VTE during hospitalization in five studies, and elevated platelet count was associated with VTE during hospitalization in one study. The risk of bias ranged from low to high for included studies. Overall, there was a paucity of high-quality prognostic studies. Studies on other biomarkers did not meet the systematic review inclusion criteria.
Conclusions
Admission D-dimer was associated with VTE diagnosis during hospitalization for COVID-19; however, prospective validation of this finding is needed to identify optimal D-dimer thresholds to guide VTE prophylaxis measures
National Program for Genetic Improvement of Feed Efficiency in Beef Cattle
Our goal is to sustainably reduce feed resources required to produce beef via the rapid development and deployment of novel nutritional, genomic and genetic improvement technologies.
We will strengthen the international competitiveness of US agriculture and enable increased food production by increasing the animal protein produced without additional feed inputs and with a reduced greenhouse gas footprint
Searching for non-Gaussianity in the VSA data
We have tested Very Small Array (VSA) observations of three regions of sky
for the presence of non-Gaussianity, using high-order cumulants, Minkowski
functionals, a wavelet-based test and a Bayesian joint power
spectrum/non-Gaussianity analysis. We find the data from two regions to be
consistent with Gaussianity. In the third region, we obtain a 96.7% detection
of non-Gaussianity using the wavelet test. We perform simulations to
characterise the tests, and conclude that this is consistent with expected
residual point source contamination. There is therefore no evidence that this
detection is of cosmological origin. Our simulations show that the tests would
be sensitive to any residual point sources above the data's source subtraction
level of 20 mJy. The tests are also sensitive to cosmic string networks at an
rms fluctuation level of (i.e. equivalent to the best-fit observed
value). They are not sensitive to string-induced fluctuations if an equal rms
of Gaussian CDM fluctuations is added, thereby reducing the fluctuations due to
the strings network to rms . We especially highlight the usefulness
of non-Gaussianity testing in eliminating systematic effects from our data.Comment: Minor corrections; accepted for publication to MNRA
Phylogenetic classification of short environmental DNA fragments
Metagenomics is providing striking insights into the ecology of microbial communities. The recently developed massively parallel 454 pyrosequencing technique gives the opportunity to rapidly obtain metagenomic sequences at a low cost and without cloning bias. However, the phylogenetic analysis of the short reads produced represents a significant computational challenge. The phylogenetic algorithm CARMA for predicting the source organisms of environmental 454 reads is described. The algorithm searches for conserved Pfam domain and protein families in the unassembled reads of a sample. These gene fragments (environmental gene tags, EGTs), are classified into a higher-order taxonomy based on the reconstruction of a phylogenetic tree of each matching Pfam family. The method exhibits high accuracy for a wide range of taxonomic groups, and EGTs as short as 27 amino acids can be phylogenetically classified up to the rank of genus. The algorithm was applied in a comparative study of three aquatic microbial samples obtained by 454 pyrosequencing. Profound differences in the taxonomic composition of these samples could be clearly revealed
Planet Populations as a Function of Stellar Properties
Exoplanets around different types of stars provide a window into the diverse
environments in which planets form. This chapter describes the observed
relations between exoplanet populations and stellar properties and how they
connect to planet formation in protoplanetary disks. Giant planets occur more
frequently around more metal-rich and more massive stars. These findings
support the core accretion theory of planet formation, in which the cores of
giant planets form more rapidly in more metal-rich and more massive
protoplanetary disks. Smaller planets, those with sizes roughly between Earth
and Neptune, exhibit different scaling relations with stellar properties. These
planets are found around stars with a wide range of metallicities and occur
more frequently around lower mass stars. This indicates that planet formation
takes place in a wide range of environments, yet it is not clear why planets
form more efficiently around low mass stars. Going forward, exoplanet surveys
targeting M dwarfs will characterize the exoplanet population around the lowest
mass stars. In combination with ongoing stellar characterization, this will
help us understand the formation of planets in a large range of environments.Comment: Accepted for Publication in the Handbook of Exoplanet
Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation
Caveolin-1 (Cav1) is an essential component of caveolae whose Src kinase-dependent phosphorylation on tyrosine 14 (Y14) is associated with regulation of focal adhesion dynamics. However, the relationship between these disparate functions remains to be elucidated. Caveola biogenesis requires expression of both Cav1 and cavin-1, but Cav1Y14 phosphorylation is dispensable. In this paper, we show that Cav1 tyrosine phosphorylation induces caveola biogenesis via actin-dependent mechanotransduction and inactivation of the Egr1 (early growth response-1) transcription factor, relieving inhibition of endogenous Cav1 and cavin-1 genes. Cav1 phosphorylation reduces Egr1 binding to Cav1 and cavin-1 promoters and stimulates their activity. In MDA-231 breast carcinoma cells that express elevated levels of Cav1 and caveolae, Egr1 regulated Cav1, and cavin-1 promoter activity was dependent on actin, Cav1, Src, and Rho-associated kinase as well as downstream protein kinase C (PKC) signaling. pCav1 is therefore a mechanotransducer that acts via PKC to relieve Egr1 transcriptional inhibition of Cav1 and cavin-1, defining a novel feedback regulatory loop to regulate caveola biogenesis
The Vehicle, Spring 1981
Vol. 22, No. 2
Table of Contents
Old Farmers at the Arcade CafeJohn Stockmanpage 4
ConfettiCathy Georgepage 6
Ode to a Corned Beef SandwichJeff Bennettpage 6
The Ice on Kirschner\u27s CreekScott Fishelpage 7
Love Poem to LindaJohn Stockmanpage 7
Grandfather\u27s PortraitJames Marshpage 8
The MassageKathleen Alakspage 9
A Driving ForceSandy Youngpage 10
King DandelionNancy Siebenpage 12
One Afternoon - Contemplating HouseworkKelli Sanderpage 13
Tent WallsAndy Sudkamppage 14
The SentinelElise Hempelpage 16
Daddy\u27s AftershaveJeff Bennettpage 16
The WeddingChris Goerlichpage 17
UntitledCarol Hansenpage 17
Treasures in the YardScott Fishelpage 18
Hitchhiker\u27s BootsAndy Sudkamppage 20
The RaffleLaura Henrypage 21
A Walk at NightJudi Jinespage 24
Morning in the DumpJeff Bennettpage 24
In Praise of Chocolate Ice CreamJohn Stockmanpage 25
Summer on the Isle of PalmsElisabeth Cristpage 26
The WaveHerbert S. Demminpage 27
RememberingJohn Kleinsteiberpage 27
PotatoJohn Stockmanpage 28
Late ShowChris Goerlichpage 30
Love in Him - JoeDebbie Klinnertpage 31
ShoeScott Fishelpage 35
The DrinkerBob Huntpage 36
The WidowGeorge Ndu Igbudupage 37
ElectricityScott Fishelpage 37
Hatchet JackB.L. Davidsonpage 39
Walking Home LateJohn Stockmanpage 41
NovemberCindy Hubbarttpage 41
On the BusLaura Henrypage 42
HaikuJames Marshpage 43
SpillwayGloria Rhoadspage 43
Art
Cover design by Linda Fraembs
PhotographRobin Scholzpage 3
PhotographRobin Scholzpage 5
PhotographMichelle Glassmeyerpage 15
PhotographRobert Schinaglpage 19
PhotographTom Robertspage 38
PhotographRobert Schinaglpage 44https://thekeep.eiu.edu/vehicle/1039/thumbnail.jp
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